We may finally know how to stop taking GLP-1s without regaining weight


Oprah Winfrey used to consider GLP-1s a “gift”.

Having long struggled with dieting, the talk show star announced in 2023 that she had begun using the drugs – officially ‘Glucagon-like peptide-1s’ but better known to the public through brand variants like Mounjaro and Ozempic – to achieve her optimum weight.

It worked, but after about a year, Winfrey stopped, eager to see if she could keep the weight off without pharmacological assistance. That decision saw her regain 20lbs (approx 9kg).

 

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